Hi there Brett,

SubQ injections for both are fine. The key is volume. If your protocol requires more than 0.6ml in volume, it is likely that the subQ injection spot may leave a hardened spot that is uncomfortable to the touch. This is generally not the case with intramuscular injections. Any volume 0.6ml or less should be just fine injected subcutaneously.

Be sure however, that your doctor is aware of your administration method/location as subQ injections tend to absorb slower than intramuscular, and impact your estradiol slightly differently.